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Ingredient guide for lubricant drops, gels, ointments & spraysUpdated 22 days ago

See also Dry Eye Shop's Guide to eye drop packaging options

Product & Package type

Active ingredients

Inactive ingredients
Preservative  Vasoconstrictor

Advanced eye relief dry eye rejuvenation

Glycerin (0.3%) Propylene glycol (1.0%)

benzalkonium chloride (0.01%), boric acid, edetate disodium, potassium chloride, purified water, sodium borate, sodium chloride. Hydrochloric acid and/or sodium hydroxide may be used to adjust pH

Bion Tears

PF vials

Dextran 70 0.1%, Hypromellose 2910 0.3%

Calcium chloride, magnesium chloride, potassium chloride, purified water, sodium bicarbonate, sodium chloride, zinc chloride, hydrochloric acid and/or sodium hydroxide and/or carbon dioxide to adjust pH.

BioTrue Hydration Boost

PF bottle

Glycerin 0.5%boric acid, erythritol, potassium chloride, purified water, sodium borate, sodium hyaluronate

Blink GelTears

Polyethylene Glycol 400 0.25%

Boric Acid; Calcium Chloride; Magnesium Chloride;Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Chlorite (OcuPure brand) as a preservative; Sodium Hyaluronate.

Blink Tears 

Polyethylene Glycol 400 0.25%

Boric Acid; Calcium Chloride; Magnesium Chloride; Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Chlorite (OcuPure Brand) as a Preservative; Sodium Hyaluronate.

Blink Tears Preservative Free 

PF vials


Polyethylene Glycol 400 0.25%

Boric Acid; Calcium Chloride; Magnesium Chloride; Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Hyaluronate.

Clear Eyes Natural Tears 

Polyvinyl alcohol 0.5%

Povidone 0.6%

Benzalkonium Chloride, Dextose, Edetate Disodium, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Citrate, Sodium Phosphate (mono- and dibasic)

Clear Eyes Outdoor Dry Eye Protection

Polyvinyl alcohol 0.5%

Povidone 0.6%

Benzalkonium ChlorideDextose, Edetate Disodium, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Citrate, Sodium Phosphate (mono- and dibasic)

Eyeganics Organic Tears

PF bottle

Glycerin 0.2% (certified organic)Sodium chloride, water
Freshkote Preservative Free 

PF bottle

Polyvinyl pyrrolidone 2.0%, Polyvinyl alcohol 2.7%

Boric acid, Edetate disodium, Ethanol, Glycerin, Lecithin, Phospholipids, Polysorbate-80, Potassium chloride, Purified water, Sodium chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Freshkote Preservative Free 

PF Vials

Polyvinyl pyrrolidone 2.0%, Polyvinyl alcohol 2.7%

Boric acid, Edetate disodium, Ethanol, 

Glycerin, Lecithin, Phospholipids, Polysorbate-80, Potassium chloride, Purified water, Sodium chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Genteal Gel (Severe)

Hypromellose 0.3%.

carbopol 980, phosphoric acid, purifed water, sodium hydroxide, sodium perborate, and sorbitol

Genteal Moderate

Dextran 70 0.1%, Glycerin 0.2%, Hypromellose 0.3%

Boric acid, calcium chloride, glycine, hydrochloric acid and/or sodium hydroxide (to adjust pH), magnesium chloride, POLYQUAD® (polyquaternium-1) 0.001% preservative, polysorbate 80, potassium chloride, purified water, sodium chloride, zinc chloride.

Genteal ointment

White petrolatum 93% Mineral oil 4%

anhydrous liquid lanolin

Genteal Tears

PF Vials

Dextran 70 0.1%, Hypromellose 2910 0.3%

Potassium Chloride, Purified Water, Sodium Borate, Sodium Chloride, May contain: Hydrochloric Acid, Sodium Hydroxide

Genteal Tears Gel DropsPolyethylene glycol 400 0.4%
Propylene glycol 0.3%
Aminomethylpropanol, Boric Acid, Edetate Disodium, Hydroxypropyl Guar, Polyquad® (Polyquaternium-1) 0.001% Preservative, Potassium Chloride, Sodium Chloride, Sorbitol And Purified Water. May Contain Hydrochloric Acid And/Or Sodium Hydroxide To Adjust Ph
Ivizia Lubricant Eye Drops

PF bottle
Povidone 0.5%Hydrochloric acid, purified water, sodium chloride, sodium hyaluronate, trehalose, tromethamine
Ivizia Lubricant Eye Gel

PF vials
Povidone 0.5%Carbomer, purified water, sodium hyaluronate, sodium hydroxide, sorbital, trehalose

Oasis Tears

Glycerin 0.22%

EDTA, potassium sorbate, sodium chloride, sodium hyaluronate, sodium hydroxide, sodium phosphate dibasic, sodium phosphate monobasic, water

Oasis Tears

PF vials

Glycerin 0.2%

Hyaluronan, sodium chloride, sodium phosphate dibasic, sodium phosphate monobasic, water.

Oasis Tears PF

PF bottle

Glycerin 0.25%

sodium chloride, sodium hyaluronate, sodium hydroxide, sodium phosphate dibasic, sodium phosphate monobasic, water

Oasis Tears Plus

PF vials

Glycerin 0.2%)

Hyaluronan, sodium chloride, sodium phosphate dibasic, sodium phosphate monobasic, water.

Oasis Tears Plus PF

PF bottle


Glycerin 0.2%

Sodium chloride, sodium hyaluronate, sodium hydroxide, sodium phosphate dibasic, sodium phosphate monobasic, water.
Optase Dry Eye Intense Drops

PF bottle
Glycerin (0.2%)Hydrochloric acidsodium hyaluronate, sorbital, trometamol, water
Optase Dry Eye SprayGlycerin 1%Sea buckthorn seed oil, sodium hyaluronate, trometamol-citrate
Optase Hylo Night
White Petrolatum (90%), lanolin (6.9%)Retinol palmitate (Vitamin A), light liquid paraffin
May contain peanut oil
Optase Hylo Relief

PF bottle
Glycerin 0.25%Borax, Boric Acid, Citric Acid anhydrous, Sodium Chlroide, Sodium Citrate Diydrate, Sodium Hyaluronate, Water
Optase MGD Advanced

PF bottle
Glycerin 0.9%Citric acid monohydrate, Polyoxyethylenesorbitan, Monooleate, Potassium Chloride, Purified Water, Sacha Inchi Seed Oil, Sodium hyaluronate, Sodium Monooleate, Trehalose, Tromethamine

Refresh Celluvisc

PF vials

Carboxymethylcellulose sodium 1%

Calcium chloride, potassium chloride, purified water, sodium chloride, and sodium lactate.

Refresh Classic

PF Vials

Polyvinyl Alcohol 1.4% Povidone 0.6%

Purified water, sodium chloride. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Refresh Digital

Carboxymethylcellulose sodium 0.5%

Glycerin 1%

Polysorbate 80 0.5%


Boric acid; carbomer copolymer type A; castor oil; erythritol; levocarnitine; purified water; PURITE® (stabilized oxychloro complex); and sodium hydroxide.

Refresh Digital PF

PF vials

Carboxymethylcellulose sodium 0.5%

Glycerin 1%

Polysorbate 80 0.5%


Boric acid; carbomer copolymer type A; castor oil; erythritol; levocarnitine; purified water; and sodium hydroxide.

Refresh LacriLube


Mineral Oil 42.5%

White Petrolatum 56.8%

Chlorobutanol and lanolin alcohols.

Refresh Liquigel

Carboxymethylcellulose sodium 1%

Boric acid, calcium chloride, magnesium chloride, potassium chloride, purified water, PURITE® (stabilized oxychloro complex), sodium borate, and sodium chloride.

Refresh Optive

PF vials
Carboxymethylcellulose sodium 0.5%
Glycerin 0.9%
Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate.
Refresh OptiveCarboxymethylcellulose sodium 0.5%
Glycerin 0.9%
Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE ® (stabilized oxychloro complex); sodium borate decahydrate; and sodium citrate dihydrate.
Refresh Optive Advanced

PF vials
Carboxymethylcellulose sodium 0.5%
Glycerin 1%
Polysorbate 80 0.5%

Boric acid; carbomer copolymer type A; castor oil; erythritol; levocarnitine; purified water; and sodium hydroxide.
Refresh Optive AdvancedCarboxymethylcellulose sodium 0.5%
Glycerin 1%
Polysorbate 80 0.5%

Boric acid; castor oil; erythritol; levocarnitine; carbomer copolymer type A; purified water; and PURITE ® (stabilized oxychloro complex) May also contain sodium hydroxide to adjust pH.

Refresh Optive Gel Drops

Carboxymethylcellulose sodium 1%,

Glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; PURITE® (stabilized oxychloro complex); sodium borate decahydrate; sodium citrate dihydrate; purified water.

Refresh Optive MEGA-3

PF vials

Carboxymethylcellulose sodium 0.5% 

Glycerin 1%

Polysorbate 80 0.5%

Boric acid; butylated hydroxyl toluene; castor oil; erythritol; flaxseed oil; levocarnitine; pemulen TR-2; polyoxyl 40 stearate; purified water; sodium hydroxide; trehalose.

Refresh Plus

PF vials

Carboxymethylcellulose sodium 0.5%

Calcium chloride; magnesium chloride; potassium chloride; purified water; sodium chloride; and sodium lactate. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Refresh PM ointment


Mineral Oil 42.5%

White Petrolatum 57.3%

Lanolin alcohols

Refresh Relieva

PF vials or PF bottle
carboxymethylcellulose sodium 0.5%
glycerin 0.9%
Boric acid; calcium chloride dihydrate; erythitrol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; sodium citrate dihydrate; and sodium hyaluronate. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Refresh Relievacarboxymethylcellulose sodium 0.5%
glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE ® (stabilized oxychloro complex); sodium borate decahydrate; sodium citrate dihydrate; and sodium hyaluronate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).
Refresh Relieva PF Xtra

PF bottle
carboxymethylcellulose sodium 0.5%
glycerin 0.9%

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; sodium citrate dihydrate; sodium hyaluronate; and trehalose. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Refresh Tears

Carboxymethylcellulose Sodium 0.5%

Oxychloro complex, Sodium Borate decahydrate, Sodium chloride, Potassium chloride, Calcium chloride dihydrate, Magnesium chloride hexahydrate, Boric acid, Sodium hydroxide to adjust pH and Purified water.

Refresh Tears PF

PF bottle
Carboxymethylcellulose Sodium 0.5%
Glycerin 0.9%
Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate.

Retaine MGD

PF vials

Light mineral oil 0.5%

Mineral oil 0.5%

Cetrimonium bromide, glycerol, poloxamer 188, tris hydrochloride, tromethamine, tyloxapol, water for injection.

Retaine PM ointment

Mineral oil (20%) 

White petrolatum (80%)

n/a

Rohto Dry AidPovidone 0.68%
Propylene glycol 0.3%
Boric acid, calcium chloride, edetate disodium, magnesium sulfate, menthol, PEG010 castor oil, poloxamer, polyaminopropyl biguanide, polyoxyl stearate, purified water, sesame oil, sodium borate.
Rohto Dry Aid

PF Vials
Povidone 0.68%
Propylene glycol 0.3%
Boric acid, calcium chloride, edetate disodium, magnesium sulfate, menthol, PEG-10 castor oil, poloxamer, polyoxyl stearate, purified water, sesame oil, sodium borate

Soothe Long Lasting Hydration

Povidone (2.0%)

benzalkonium chloride (0.005%), boric acid, edetate disodiumdihydrate, purified water, sodium borate, sodium chloride, tyloxapol. Hydrochloric acid and/or sodium hydroxide may be used to adjust pH.

Soothe Lubricant Eye Drops Hydration

Povidone (1.25%)

boric acid, potassium chloride, sodium borate and sodium chloride; preserved with edetate disodium 0.1% and sorbic acid 0.1%

Soothe Lubricant Eye Drops Preservative Free 

PF Vials

Glycerin 0.6%) Propylene Glycol (0.6%)

boric acid, hydroxyalkylphosphonate, purified water, sodium alginate, sodium borate

Soothe Maximum Hydration

Povidone (2.0%)

benzalkonium chloride (0.005%), boric acid, edetate disodiumdihydrate, purified water, sodium borate, sodium chloride, tyloxapol. Hydrochloric acid and/or sodium hydroxide may be used to adjust pH.

Soothe Night Time Ointment

Mineral oil (20%)

White petrolatum (80%)

n/a


Soothe XP Emollient 

Light mineral oil (1.0%), Mineral oil (4.5%)

boric acid, edetate disodium, octoxynol-40, polyquaternium-1 (preservative), polysorbate 80, purified water, sodium borate decahydrate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).

Soothe XP Emollient PF

PF vials

Light mineral oil (1.0%)

Mineral oil (4.5%)

boric acid, edetate disodium, octoxynol-40, polysorbate 80, purified water, sodium borate decahydrate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).

Systane

PF vials
Polyethylene Glycol 400 0.4%,

Propylene Glycol 0.3%

Boric acid, calcium chloride, hydroxypropyl guar, magnesium chloride, potassium chloride, purified water, sodium chloride, zinc chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
SystanePolyethylene Glycol 400 0.4%,

Propylene Glycol 0.3%


Boric acid, calcium chloride, hydroxypropyl guar, magnesium chloride, polyquaternium-1 as a preservative, potassium chloride, purified water, sodium chloride, zinc chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Systane Balance
Propylene Glycol 0.6%
Boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, POLYQUAD® (polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Complete

Propylene Glycol 0.6%

Boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxl 40 Stearate, POLYQUAD (polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbital and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Complete

PF vials or PF bottle
Propylene Glycol 0.6%Boric acid, dimyristoyl phosphatidylglycerol, hydroxypropyl guar mineral oil, polyoxl 40 stearate, sorbitan tristearate, sorbital and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Gel Drops

Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3%

Aminomethylpropanol, boric acid, edetate disodium, hydroxypropyl guar, POLYQUAD® (polyquaternium-1) 0.001% preservative, potassium chloride, sodium chloride, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Hydration PF

PF vials or PF bottle
Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3%aminomethylpropanol, boric acid, hydroxypropyl guar, potassium chloride, purified water, sodium borate, sodium chloride, sodium hyaluronate, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Systane Lubricant Eye Gel

Hypromellose (0.3%)

Carbopol 980, phosphonic acid, purified water, sodium perborate and sorbitol. May contain sodium hydroxide to adjust pH.

Systane Nighttime ointment

White petrolatum 94% 

Mineral oil 3%

Anhydrous Liquid Lanolin 3%.

Systane Ultra

PF vials or PF bottle

Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3%
Aminomethylpropanol, boric acid, hydroxypropyl guar, potassium chloride, purified water, sodium chloride, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Systane Ultra
Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3%
Aminomethylpropanol, boric acid, hydroxypropyl guar, POLYQUAD* (polyquaternium-1) 0.001% preservative, potassium chloride, purified water, sodium chloride, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
TheraTears Dry Eye TherapySodium Carboxymethyl Cellulose (0.25%)
Borate Buffers, Calcium Chloride, Dequest, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Perborate, Sodium Phosphate
TheraTears Dry Eye Therapy

PF vials

Sodium Carboxymethyl Cellulose (0.25%)
Borate Buffers, Calcium Chloride, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride and Sodium Phosphate.

TheraTears EXTRA Dry Eye Therapy

Sodium Carboxymethyl Cellulose (0.25%)

Boric Acid Calcium Chloride, Dequest, Potassium Chloride, Sodium Bicarbonate, Sodium Borate, Sodium Chloride, Magnesium Chloride, Sodium Perborate, Sodium Phosphate Trehalose, Water for Injection

TheraTears EXTRA

PF Vials
Sodium Carboxymethyl Cellulose (0.25%)
Boric acid, calcium chloride, hydrochlorid acid*, magnesium chloride, potassium chloride, sodium bicarbonate, sodium borate, sodium chloride, sodium hydroxide*, sodium phosphate, trehalose and water for injection. *May contain these ingredients to adjust pH.

TheraTears nighttime dry eye therapy (gel)

PF vials

Sodium Carboxymethyl Cellulose (1%)

Borate Buffer, Calcium Chloride, Magnesium Chloride, Potassium Chloride, Water (Purified), Sodium Bicarbonate (Baking Soda), Sodium Chloride, Sodium Phosphate

Visine Dry Eye Relief

Glycerin 0.2%

Hypromellose 0.2%

Polyethylene glycol 400 1%

ascorbic acid, benzalkomium chloride, boric acid, dextrose, disodium phosphate, glycine, magnesium chloride, potassium chloride, purified water, sodium borate, sodium chloride, sodium citrate, sodium lactate

Visine Tired Eye Dry Eye Relief

Glycerin 0.2%

Hypromellose 0.36%

Polyethylene glycol 400 1%

ascorbic acid, boric acid, dextrose, glycine, magnesium chloride, polyquaternium-42, potassium chloride, purified water, sodium borate, sodium chloride, sodium citrate, sodium lactate, sodium phosphate dibasic



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